Colangiopancreatografía retrógrada endoscópica asistida por enteroscopia de doble balón en un paciente con gastrectomía total y reconstrucción en Y-de-Roux: reporte de caso / Double-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography in a patient with total gastrectomy and roux-en-y reconstruction: A case report

Resumen La colangiopancreatografía retrógrada endoscópica (CPRE) es un procedimiento útil en el manejo de enfermedades biliopancreáticas. Los pacientes con alteración anatómica del tracto gastrointestinal representan un desafío técnico por múltiples razones. Con técnicas como la enteroscopia de doble balón (EDB) es posible realizar una CPRE en estos pacientes. El caso que se presenta es el primero de este tipo publicado en Colombia sobre una paciente con gastrectomía total con reconstrucción en Y-de-Roux y coledocolitiasis.

Abstract Endoscopic retrograde cholangiopancreatography (ERCP) is a valuable procedure in managing biliopancreatic diseases. Patients with anatomical alteration of the gastrointestinal tract represent a technical challenge for multiple reasons. With techniques such as double-balloon enteroscopy (DBE), it is possible to perform ERCP in these patients. The case was first published in Colombia on a female patient with total gastrectomy with Roux-en-Y reconstruction and choledocholithiasis.

Calidad de vida posterior a gastrectomía total laparoscópica versus abierta en cáncer gástrico / Quality of life after -laparoscopic versus open total gastrectomy in gastric cancer

Resumen Introducción: En los últimos años, la gastrectomía laparoscópica ha aparecido como una técnica quirúrgica con resultados oncológicos comparables a la técnica abierta, pero existe poca evidencia en cuanto a la calidad de vida posoperatoria de estos pacientes. Objetivo: Evaluar la calidad de vida posoperatoria de pacientes sometidos a gastrectomía total laparoscópica (GTL) en comparación a gastrectomia total abierta (GTA) en cáncer gástrico. Materiales y Método: Estudio retrospectivo, observacional en Hospital Militar de Santiago, entre enero de 2015 y junio de 2020. Se les aplicó 2 encuestas validadas para Chile: EORTC QLQ-30 y EORTC QLQ-OG25. Resultados: Se obtuvieron 60 pacientes; 30 sometidos a GTL y 30 a GTA. Promedio edad fue 66,3 ± 11 años para GTL y 68,2 ± 11 años en GTA (p = 0,5). Se obtuvo un score en GTL versus GTA: global 83,3 y 80,2 (p = 0,6), sintomático 17,1 y 25,5 (p = 0,2) y score funcional 87,9 y 70,9 (p = 0,03). Posterior a eso obtuvimos en funcionalidad GTL versus GTA; física 92,2 versus GTA 73,1 (p = 0,04), emocional 84,1 versus 78,5 (p = 0,6), cognitiva 84,9 versus 79,0 (p = 0,3) y social 80,9 versus 72,2 (p = 0,4). Al analizar síntomas destaco; fatiga 14,6 versus 33,1 (p = 0,04) y dolor 13,4 versus 24,3 (p = 0,05). Finalmente, en síntomas digestivos altos obtuvimos en disfagia 0,84 GTL versus 17,3 GTA (p = 0,04). Conclusión: La GTL logra resultados comparables a GTA en calidad de vida e incluso ofrece ventajas significativas en funcionalidad física como también en síntomas como dolor, fatiga y disfagia.

Introduction: In recent years, laparoscopic gastrectomy has appeared as a surgical technique with oncological results comparable to the open technique, but there is little evidence regarding the postoperative quality of life of these patients. Objective: To evaluate the postoperative quality of life of patients undergoing laparoscopic total gastrectomy (LTG) compared to open total gastrectomy (OTG) in gastric cancer. Materials and Method: Prospective, observational study at Hospital Militar of Santiago, between January 2015 and June 2020. Two surveys validated for Chile were applied: EORTC QLQ-30 and EORTC QLQ-OG25. Results: 60 patients were obtained; 30 subjected to LTG and 30 to OTG. Average age was 66.3 ± 11 years for LTG and 68.2 ± 11 years for OTG (p = 0.5). A score was obtained in LTG versus OTG: global 83.3 and 80.2 (p = 0.6), symptomatic 17.1 and 25.5 (p = 0.2) and functional score 87.9 and 70.9 (p = 0.03). After that we got LTG versus OTG functionality; physical 92.2 versus 73.1 (p = 0.04), emotional 84.1 versus 78.5 (p = 0.6), cognitive 84.9 versus 79.0 (p = 0.3) and social 80.9 versus 72.2 (p = 0.4). When analyzing symptoms I highlight; fatigue 14.6 versus 33.1 (p = 0.04) and pain 13.4 versus 24.3 (p = 0.05). Finally, in upper digestive symptoms, we obtained 0.84 LTG versus 17.3 OTG in dysphagia (p = 0.04). Conclusion: LTG achieves results comparable to OTG in quality of life and even offers significant advantages in physical functionality as well as symptoms such as pain, fatigue and dysphagia.

Margen positivo (R1) en la biopsia intraoperatoria durante una gastrectomía total por cáncer gástrico / Positive margin (R1) in the intraoperative biopsy during a total gastrectomy for gastric cancer

Resumen El cáncer gástrico es una patología de alta incidencia en Chile. Afortunadamente es baja la incidencia de márgenes R1 cuando se realiza una cirugía con intención curativa. Al tener un tumor subcardial o cardial es perentorio realizar una biopsia rápida (intraoperatoria), en caso que ésta resulte positiva, es difícil tomar una decisión sobre qué realizar a continuación, ya que el realizar una esofagoyeyunoanastomosis intratorácica aumenta el riesgo quirúrgico. Para esto, es de suma importancia tener la información de las características histopatológicas del tumor, el riesgo de filtración, la recurrencia, la sobrevida, las terapias adyuvantes y la realidad país. Se realizó una revisión de la literatura con el fin de poder guiar la toma de decisiones.

Gastric cancer is a pathology with a high incidence in Chile, fortunately, the incidence of R1 margins is low when performing surgery with curative intent. When having a sub cardial or cardial tumor, it is essential to perform a rapid (intraoperative) biopsy, if this is positive when cutting the esophagus just under the pillars, it is difficult to make the decision of what to do next, since performing an inthrathoracic esophagojejunostomy increases the surgical risk. For this, it is very important to have information about the histopathological characteristics of the tumor, the leakage risk, there currence, the survival, the adjuvant therapies and the reality of the country. A review of the literature was done in order to guide the decisions.

Resultados de la manometría del cuerpo esofágico y del asa de yeyuno en pacientes operados por cáncer gástrico con gastrectomía total 5 años después de la cirugía / Esophageal manometry in patients with total gastrectomy 5 years after surgery

Resumen Introducción: La técnica de elección para la reconstrucción del tránsito intestinal después de una gastrectomía total es la esófago-yeyuno anastomosis en Y de Roux, la cual evita el reflujo de jugo digestivo alcalino. El objetivo del presente estudio es el de analizar la motilidad del esófago y del asa de yeyuno en pacientes operados con gastrectomía total por cáncer gástrico. Pacientes y método: Se estudió prospectivamente una muestra de 17 pacientes intervenidos mediante gastrectomía total 5 años atrás. En todos ellos se realizaron manometrías esofágicas de alta resolución incluyendo los primeros 7 cm del asa de yeyuno. Resultados: Los resultados de la manometría demostraron motilidad esofágica normal a excepción de la presión máxima intrabolo, la cual se encontraba aumentada en todos los pacientes. La motilidad del asa de yeyuno fue desordenada e inefectiva. Conclusiones: La motilidad del cuerpo esofágico es normal 5 años después de la gastrectomía total. Sin embargo, la presión intrabolo máxima se encuentra aumentada; la causa más probable de este hecho estaría constituida por el asa de yeyuno, que ejerce resistencia al paso del bolo debido a que presenta una actividad motora desordenada y poco propulsiva. El impacto clínico de este hecho es, sin embargo, poco importante.

Abstract Introduction: The most preferred technique to reconstruct the intestinal transit after total gastrectomy for gastric cancer is the Roux-en-Y esophagus-gastrostomy which prevents the reflux of alkaline intestinal juice. The purpose of this study was to analyze the esophageal motility and the motility of the jejunal loop in patients subjected to total gastrectomy. Patients and method: A prospective sample of 17 total gastrectomy patients operated on 5 years before was studied using high resolution esophageal manometry including the first 7 cm of the jejunal loop. Results: Manometry results showed normal esophageal body motility with the exception of the maximum intrabolus pressure that was elevated in all patients. The jejunal loop motility was disordered and ineffective. Conclusions: Esophageal body motility was normal 5 years after the surgical procedure. However, maximum intrabolus pressure was elevated and the most plausible reason would be the jejunal loop that exerts resistance to the bolus passage due to its ineffective motility. However, this fact does not have a significant clinical impact.

Comparison of laparoscopic total gastrectomy and laparotomic total gastrectomy for gastric cancer / Comparação entre a gastrectomia total laparoscópica e a gastrectomia total laparotômica para o câncer gástrico

BACKGROUND: The use of laparoscopy for the treatment of gastric cancer suffered some resistance among surgeons around the world, gaining strength in the past decade. However, its oncological safety and technical feasibility remain controversial. AIM: To describe the results from the clinical and anatomopathological point of view in the comparative evaluation between the surgical videolaparoscopic and laparotomic treatments of total gastrectomy with linphadenectomy at D2, resection R0. METHOD: Retrospective analyses and comparison data from patients submitted to total gastrectomy with D2 linphadenectomy at a sole institution. The data of 111 patients showed that 64 (57,7%) have been submitted to laparotomic gastrectomy and 47 (42,3%) to gastrectomy entirely performed through videolaparoscopy. All variables related to the surgery, post-operative follow-up and anatomopathologic findings have been evaluated. RESULTS: Among the studied variables, videolaparoscopy has shown a shorter surgical time and a more premature period for the introduction of oral and enteral nourishment than the open surgery. As to the amount of dissected limph nodes, there has been a significant difference towards laparotomy with p=0,014, but the average dissected limph nodes in both groups exceed 25 nodes as recommended by the JAGC. Was not found a significant difference between the studied groups as to age, ASA, type of surgery, need for blood transfusion, stage of the disease, Bormann classification, degree of differentiation, damage of the margins, further complications and death. CONCLUSION: The total gastrectomy with D2 lymphadenectomy performed by laparoscopy presented the same benefits known of laparotomy and with the advantages already established of minimally invasive surgery. It was done with less surgical time, less time for re-introduction of the oral and enteral diets and lower hospitalization time compared to laparotomy, without increasing postoperative ...

RACIONAL: A utilização da videolaparoscopia para o tratamento das neoplasia gástricas sofreu certa resistência entre os cirurgiões ao redor do mundo, ganhando força na década passada. Porém, sua segurança oncológica e viabilidade técnica continuam controversas. OBJETIVO: Demonstrar os resultados do ponto de vista clínico e anatomopatológico na avaliação comparativa entre o tratamento cirúrgico videolaparoscópico e laparotômico da gastrectomia total com linfadenectomia a D2, ressecção R0. MÉTODOS: Estudo retrospectivo dos dados dos prontuários dos pacientes submetidos à gastrectomia total com lindadenectomia a D2, em uma única instituição. Dos 111 prontuários, 64 (57,7%) foram submetidos à gastrectomia laparotômica e 47 (42,3%) à gastrectomia totalmente vídeolaparoscópica. Foram avaliadas variáveis relacionadas ao ato cirúrgico, a evolução pós-operatória e a achados anatomopatológicos. RESULTADOS: A técnica videolaparoscópica demonstrou tempo cirúrgico menor e período para re-introdução alimentar oral e enteral mais precoce que a operação laparotômica. Quanto ao número de linfonodos dissecados, houve diferença significante a favor da laparotômica (p=0,014); porém, a média de linfonodos dissecados em ambos os grupos ultrapassou os 25 preconizados pela JAGC. Não foi encontrada diferença significante entre os grupos estudados no que diz respeito à idade, gênero, ASA, tipo de operação, necessidade de hemotransfusão, estadiamento, classificação de Bormann, grau de diferenciação, comprometimento de margens, complicações e óbito. CONCLUSÕES: A gastrectomia total com linfadenectomia a D2 realizada por videolaparoscopia apresenta os mesmos benefícios conhecidos da cirurgia laparotômica e com as vantagens já estabelecidas da cirurgia minimamente invasiva. Ela apresentou menor tempo cirúrgico, menor tempo para a re-introdução das dietas oral e enteral e tempo de alta menor em relação à laparotômica, sem aumentar as complicações pós-operatórias. .

Blood count and C-reactive protein evolution in gastric cancer patients with total gastrectomy surgery / Evolução do hemograma e proteína C-reativa em pacientes com câncer gástrico operados por gastrectomia total

BACKGROUND: The complete blood count (CBC) and C-reactive protein (CRP) are useful inflammatory parameters for ruling out acute postoperative inflammatory complications. AIM: To determine their changes in gastric cancer patients submitted to total gastrectomy. METHODS: This is a prospective study, with 36 patients with gastric cancer who were submitted to elective total gastrectomy. On the first, third and fifth postoperative day (POD), blood count and CRP changes were assessed. Patients with postoperative complications were excluded. RESULTS: Twenty-one (58%) were men and 15 (42%) women. The mean age was 65 years. The leukocytes peaked on the 1st POD with a mean of 13,826 u/mm³, and decreased to 8,266 u/mm³ by the 5th POD. The bacilliforms peaked on the 1st POD with a maximum value of 1.48%. CRP reached its maximum level on the 3rd POD with a mean of 144.64 mg/l±44.84. Preoperative hematocrit (HCT) was 35% and 33.67% by the 5th POD. Hemoglobin, showed similar values. CONCLUSIONS: Leukocytes increased during the 1st POD but reached normal values by the 5th POD. CRP peaked on the 3rd POD but did not reach normal values by the 5th POD. .

RACIONAL: O hemograma completo (CBC) e a proteína C-reativa (PCR) são úteis para excluir parâmetros inflamatórios e complicações inflamatórias agudas pós-operatórias. OBJETIVO: Determinar mudanças nesses parâmetros em pacientes com câncer gástrico submetidos à gastrectomia total. MÉTODOS: Estudo prospectivo com 36 pacientes com câncer gástrico submetidos todos à gastrectomia eletiva. No primeiro, terceiro e quinto dias pós-operatórios (PO), alterações do hemograma e as mudanças de PCR foram avaliadas. Os pacientes com complicações pós-operatórias foram excluídos. RESULTADOS: Vinte e um (58%) eram homens e 15 (42%) mulheres. A média de idade era de 65 anos. Os leucócitos atingiram o pico no primeiro PO com média de 13.826 u/mm³​​, e decresceram para 8.266 u/mm³ no quinto. Os bastonetes atingiram o pico no primeiro PO com valor máximo de 1,48%. O nível máximo da PCR foi no 3º PO, com média de 144,64 mg/l±44,84. O hematócrito pré-operatório (HCT) foi de 35% e de 33,67% até o 5o PO. A hemoglobina não apresentou alterações. CONCLUSÕES: Houve aumento de leucócitos no 1o PO mas atingiram valores normais até o 5o PO. PCR atingiu o pico no 3º PO, mas não atingiu os valores normais até o quinto. .

Valoración del análisis de la pieza operatoria en el cáncer gástrico por el cirujano / Concordance between the surgical piece observation by the surgeon and final pathological report for gastric cancer

Background: The systematic dissection of the surgical piece, performed by the surgeon during surgical treatment of gastric cancer, gives information about borders and lymph node involvement. Aim: To determine the concordance between the findings of the surgeon during initial dissection and the final pathological report. Material and Methods: Prospective study of 48 patients aged 64 +/- 10 years (74 percent males) subjected to curative surgery for gastric cancer. Patients were staged according to 2010 TNM classification. Stomach size from the lesser curvature, oral and caudal limits, macroscopic aspect, tumor diameter and lymph node involvement were determined by the surgeon observing the surgical piece. The concordance of this observation with the final pathological report was assessed. Results: Fifty nine percent of patients were subjected to a total gastrectomy and there was a mean of 30 lymph nodes excised. There was a good concordance between surgeon observation and final pathological report for tumor depth (Kappa = 0.64), macroscopic aspect (Kappa = 0.69) and tumor size (Lin = 0.84). There was a bad concordance for lymph node involvement (Kappa = 0.21). The percentage of retraction of lesser curvature length was 24 percent, 30 percent for oral and 22 percent for caudal limits. Conclusions: There is a good concordance between surgeon observation and pathological report for macroscopic aspect, tumor size and depth but the concordance for lymph node involvement is bad.

Introducción: La disección de la pieza operatoria (PO) en forma sistemática en la cirugía por cáncer gástrico (CG) permite al cirujano obtener información de los bordes, compromiso linfonodal y estandarizar. Objetivos: 1) Determinar la concordancia de los hallazgos de la PO disecada por el cirujano y el informe patológico final; 2) Determinar el porcentaje de retracción del estómago; 3) Mostrar una forma de registrar la PO en el CG. Material y Método: Estudio prospectivo de los pacientes operados con intención curativa desde septiembre de 2009 hasta mayo de 2010. Se etapificó con TNM de 2010. De la PO se registró el tamaño del estómago por curvatura menor, límite oral (LO), límite caudal (LC), profundidad, aspecto macroscópico, diámetro tumoral, grupos ganglionares comprometidos y cantidad de ganglios comprometidos. Se compararon estas variables con el informe patológico. El análisis de concordancia se realizó con el test de Kappa y el test de Lin. Resultados: Fueron estudiados 48 pacientes, 74 por ciento hombres, la edad promedio fue 63,7 años (DE 9,8), 59,5 por ciento fueron gastrectomías totales. El promedio de ganglios disecados fue 30,18 (DE 11,8). Se obtiene una buena concordancia para la profundidad del tumor (Kappa = 0,64), aspecto macroscópico (Kappa = 0,69) y tamaño tumoral (Lin = 0,84). Y una mala concordancia para el compromiso ganglionar (Kappa = 0,21). El porcentaje de retracción del largo por curvatura menor fue 24,3 por ciento, del LO fue 30,1 por ciento, del LC fue 22 por ciento. Conclusión: La concordancia de la PO es buena en la profundidad, aspecto macroscópico del tumor y diámetro tumoral, pero es mala en el compromiso ganglionar. Se determina que la retracción del estómago es mayor al 24 por ciento.

Complicações pós-operatórias após gastrectomia total no câncer gástrico: análise de 300 doentes / Postoperative complications after total gastrectomy in the gastric cancer: analysis of 300 patients

RACIONAL: A gastrectomia total é considerada um procedimento de alto nível de complexidade, apresenta taxas de complicações elevadas, tanto locais como gerais, pois os doentes na sua maioria estão com as condições clínicas e nutricionais comprometidas pela doença. OBJETIVOS: analisar os resultados imediatos e complicações da gastrectomia total no período de 1972 a 2007. MÉTODOS: Foram revisados os prontuários médicos de 300 doentes portadores de adenocarcinoma gástrico, subdivididos em dois períodos: 1972 a 1992 - compreendendo 108 doentes (36 por cento) e 1993 a 2007 - compreendendo 192 doentes (64 por cento). Eram 67,3 por cento do sexo masculinos, 70,7 por cento brancos e com faixa etária variando de 25 a 86 anos (média de 63,4 anos). As lesões estavam localizadas em cárdia - 40 casos (13,3 por cento); fundo gástrico - 83 casos (27,6 por cento); corpo gástrico - 77 casos (25,6 por cento); linite plástica - 45 casos (15 por cento); côto gástrico - 33 casos (11 por cento) e antro/corpo gástrico - 22 casos (7,3 por cento). A gastrectomia total ampliada com linfadenectomia até nível D2 foi realizada em 246 casos (82 por cento). RESULTADOS: A técnica de reconstrução mais utilizada foi a anastomose esôfago-jejunal término-lateral em Y-Roux em 257 doentes (86,7 por cento). As complicações gerais no período de 1972-92 totalizaram 47 casos (43,5 por cento), compreendendo principalmente as respiratórias (28 casos - 25,9 por cento) e as urinárias (10 casos - 9,2 por cento). No período 1993-2007 totalizaram 48 casos (25 por cento), principalmente complicações respiratórias (27 casos - 14 por cento), seguidas também das urinárias (12 casos - 6,2 por cento). No período de 1972-92 estas complicações locais totalizaram 45 casos (30,8 por cento) e no período de 1993-2007 atingiram 28 casos (14,5 por cento), sendo as fistulas digestivas as mais frequentes. A mortalidade operatória até o 30º dia foi de 18 casos (6 por cento), sendo que no período de 1972-92 totalizou...

BACKGROUND: A total gastrectomy is considered a procedure with a high level of complexity, has high complication rates, both local and general, because patients are mostly with clinical conditions and nutritional compromised by disease. AIM: To analyse the results and complications of the total gastrectomy in gastric cancer in the period from 1972 to 2007. METHODS: Were reviewed the medical records of 300 patients with gastric adenocarcinoma, divided into two periods: from 1972 to 1992 - comprising 108 patients (36 percent) and from 1993 to 2007 - comprising 192 patients (64 percent). They were 67.3 percent males, 70.7 percent whites, with ages ranging from 25 to 86 years (mean 63.4 years). The lesions were located in cardia - 40 cases (13.3 percent), gastric fundus - 83 cases (27.6 percent), gastric body - 77 cases (25.6 percent); plastic linitis- 45 cases (15 percent); gastric stump - 33 cases (11 percent) and antrum and body gastric - 22 cases (7.3 percent). A total gastrectomy with extended lymphadenectomy to level D2 was performed in 246 cases (82 percent). RESULTS: The reconstruction technique used was the esophagus-jejunal anastomosis end-to-side Roux-en-Y in 257 patients (86.7 percent). The general complications in the period from 1972 to 1992 totalized 47 cases (43.5 percent), mainly involving the respiratory (28 cases - 25.9 percent) and urinary tract (10 cases - 9.2 percent). In the period from 1993 to 2007 amounted to 48 cases (25 percent), mainly respiratory complications (27 cases - 14 percent), followed by urinary (12 cases - 6.2 percent). The local complications from 1972 to 1992 totalized 45 cases (30.8 percent) and in the period from 1993 to 2007 amounted to 28 cases (14.5 percent), being the most frequent the digestive fistulas. The operative mortality through 30 days was 18 cases (6 percent), while in the period from 1972 to 92 a total of 12 cases (11.1 percent) and in the period from 1993 to 2007 were 7 cases (3.6 percent)...

Comparación entre nutrición enteral precoz y nutrición enteral tardía en el estado nutricional de pacientes gastrectomizados / Comparison between early enteral nutrition and late enteral nutrition in the nutritional status of patients with gastrectomy

Enteral nutrition (EN) is an effective method to meet the nutritional requirements in patients who have a deteriorated nutritional status. Objectives: To compare clinical and nutritional performance of two groups: Early Enteral Nutrition (EEN) versus Late Enteral Nutrition (LEN) of patients undergoing to total gastrectomy for gastric cancer. Material and Methods: 18 patients with resectable gastric cancer were studied with anthropometric, functional and biochemical parameters to assess nutritional status in the preoperative and postoperative period. They received a polimeric enteral formula (1 kcal/ml) in the postoperative period. They were randomly assigned to the type of nutrition (early or late). Results: The group with EEN had a significant improvement in the bicipital fold adequacy percentage and dynamometry. The LEN group had a significant decrease of albumin. The bloating was more frequent in the group with EEN. Conclusion: Early enteral nutrition is a safe nutritional support, effective and that brings nutritional benefits compared with late enteral nutrition in patients undergoing to total gastrectomy for gastric cancer.

La nutrición enteral (NE) es un método efectivo para cubrir los requerimientos nutricionales en pacientes que presentan un estado nutricional deteriorado. Objetivos: Comparar la Nutrición Enteral Precoz (NEP) versus Nutrición Enteral Tardía (NET) en la evolución clínica y nutricional de pacientes sometidos a gastrectomía total por Cáncer Gástrico. Material y Método: 18 pacientes con cáncer gástrico resecable, fueron estudiados con parámetros antropométricos, funcionales y bioquímicos que evalúan el estado nutricional, en el período preoperatorio y postoperatorio. Recibieron una fórmula enteral polimérica (1 kcal/ml) en el período postoperatorio. De manera aleatoria fueron asignados al tipo de nutrición (precoz o tardía). Resultados: El grupo con NEP presentó mejoría significativa del porcentaje de adecuación del pliegue bicipital y dinamometría. El grupo con NET presentó disminución significativa de la albuminemia. La distensión abdominal fue más frecuente en grupo con NEP. Conclusión: La Nutrición Enteral Precoz es un soporte nutricional seguro, eficaz y que trae consigo ventajas nutricionales en comparación con la Nutrición Enteral Tardía en el grupo de pacientes gastrectomizados totales por presentar cáncer gástrico.

Tumor del estroma gastrointestinal y cirugía / Tumor of the gastrointestinal stroma and surgery

Los tumores del estroma gastrointestinal son los tumores mesenquimales más frecuentes del tubo digestivo. Se estudiaron 4 pacientes operados en el Hospital ®Hermanos Ameijeiras¼ entre junio de 2004 y marzo de 2007. En un caso de localización gástrica se realizó la resección primaria del tumor y en los restantes la cirugía se realizó después de una respuesta parcial con Imatinib Mesylateâ. Para la resección total del tumor fue necesaria una gastrectomía total con esofagogastrectomía en Y de Roux y una proctosigmoidectomía con conservación del esfínter anal y colostomía terminal transitoria. Los de localización gástrica tuvieron una evolución satisfactoria, y uno de ellos con recurrencia de la enfermedad. El paciente con tumor de localización rectal falleció después de un shock séptico. La cirugía constituye para estos enfermos la única posibilidad de curación, incluso en casos de tumores inicialmente irresecables.

The tumors of the gastrointestinal stroma are the most common mesenchimal tumors of the digestive tube. Four patients operated on at ®Hermanos Ameijeiras¼ Hospital from June 2004 to March 2007 were studied. Primary resection of the tumor was performed in a case of gastric localization, whereas in the rest surgery was carried out after a partial response with Imatinib Mesylateâ. A total gastrectomy with Roux en-Y esophageal gastrectomy and a proctosigmoidectomy with conservation of the anal sphincter and transient terminal colostomy were necessary for the total resection of the tumor. Those of gastric localization had a satisfactory evolution, and one of them with recurrence of the disease. The patient with tumor of rectal localization died alter a septic shock. Surgery is the only possibility of cure for these patients, even in the cases of initially unresectable tumors.